KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
31.52
Human Site:
Y121
Identified Species:
46.22
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
Y121
R
M
L
M
N
A
R
Y
F
L
E
M
S
D
T
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
Y121
R
M
L
M
N
A
R
Y
F
L
E
M
S
D
T
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
Y584
K
V
L
M
S
V
Q
Y
F
L
E
D
V
D
C
Dog
Lupus familis
XP_849292
706
81555
Y121
R
M
L
M
N
A
R
Y
F
L
E
M
S
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
Y121
R
M
L
M
N
A
R
Y
F
L
E
M
S
D
T
Rat
Rattus norvegicus
Q9WTQ0
707
81732
Y121
R
M
L
M
N
A
R
Y
F
L
E
M
S
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
Y121
R
L
L
M
N
A
R
Y
F
L
E
M
S
D
T
Chicken
Gallus gallus
NP_001006133
699
80179
Y120
K
V
L
M
A
V
Q
Y
F
L
E
D
A
D
C
Frog
Xenopus laevis
Q7LZQ8
671
76506
D113
Y
S
S
P
T
F
C
D
H
C
G
S
L
L
Y
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
Y122
D
H
C
G
S
L
L
Y
G
L
I
H
Q
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
H114
L
V
V
H
K
K
C
H
L
S
V
V
S
K
C
Honey Bee
Apis mellifera
XP_394743
624
71014
F114
G
H
K
L
V
A
K
F
F
S
Q
P
T
F
C
Nematode Worm
Caenorhab. elegans
P34722
704
80280
T121
N
G
R
I
L
A
Q
T
R
H
L
K
N
A
P
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
G113
W
G
L
V
G
T
Q
G
Y
R
C
M
E
C
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
M289
S
L
I
P
V
A
I
M
W
L
L
L
S
D
I
Red Bread Mold
Neurospora crassa
P87253
1142
127954
A216
K
I
V
L
L
K
Q
A
L
K
R
Y
E
E
L
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
100
46.6
100
N.A.
100
100
N.A.
93.3
46.6
0
13.3
N.A.
6.6
13.3
6.6
13.3
P-Site Similarity:
100
100
73.3
100
N.A.
100
100
N.A.
100
73.3
0
20
N.A.
33.3
46.6
26.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
7
57
0
7
0
0
0
0
7
7
0
% A
% Cys:
0
0
7
0
0
0
13
0
0
7
7
0
0
7
25
% C
% Asp:
7
0
0
0
0
0
0
7
0
0
0
13
0
57
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
50
0
13
7
7
% E
% Phe:
0
0
0
0
0
7
0
7
57
0
0
0
0
7
0
% F
% Gly:
7
13
0
7
7
0
0
7
7
0
7
0
0
7
0
% G
% His:
0
13
0
7
0
0
0
7
7
7
0
7
0
0
0
% H
% Ile:
0
7
7
7
0
0
7
0
0
0
7
0
0
0
7
% I
% Lys:
19
0
7
0
7
13
7
0
0
7
0
7
0
7
0
% K
% Leu:
7
13
57
13
13
7
7
0
13
63
13
7
7
7
7
% L
% Met:
0
32
0
50
0
0
0
7
0
0
0
44
0
0
7
% M
% Asn:
7
0
0
0
38
0
0
0
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
13
0
0
0
0
0
0
0
7
0
0
7
% P
% Gln:
0
0
0
0
0
0
32
0
0
0
7
0
7
0
0
% Q
% Arg:
38
0
7
0
0
0
38
0
7
7
7
0
0
0
0
% R
% Ser:
7
7
7
0
13
0
0
0
0
13
0
7
50
0
0
% S
% Thr:
0
0
0
0
7
7
0
7
0
0
0
0
7
0
38
% T
% Val:
0
19
13
7
13
13
0
0
0
0
7
7
7
0
0
% V
% Trp:
7
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
57
7
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _